| abstract |
Compound of formula A: in which: Q is selected from the group consisting of CO2H or a salt thereof, CONR'R '', SO3H or a salt thereof, and SO2NR'R ''; P is a group of formula (a); R1 is selected from the group consisting of Br, CF3, CHF2, and CH2F; R3 is H or CH3; R 'and R' 'are independently selected from the group consisting of H, C1-C10 alkyl, and C1-C10 alkyl substituted with one or more OR, CO2R, NHR, NR2, or CF3 groups in which R is H or C1-C10 alkyl, or R 'and R' 'together with the nitrogen atom to which they are attached form a 4, 5 or 6 membered heterocyclic ring; R0 is selected from the group consisting of Cl, Br, CF3 and methyl; Rp is selected from the group consisting of halogen, methyl, ethyl, propyl, isopropyl, cyclopropylmethyl, and C3-C6 cycloalkyl; and R4, R5 and R6 are each H. |