| abstract |
A compound of the formula I, ** Formula ** wherein R1 is hydrogen; or amino that is unsubstituted or monosubstituted with alkyl or cycloalkyl; R2 is an unsubstituted or substituted aryl or unsubstituted or substituted heteroaryl; R3 is hydrogen, halogen, alkyl, alkoxy or cyano; R4 is unsubstituted or substituted aryl or unsubstituted or substituted heteroaryl; and R5 is hydrogen, methyl or methyl substituted with halogen; with the proviso that if R4 is unsubstituted or substituted pyrazolyl then R1 is amino that is unsubstituted or monosubstituted with alkyl or cycloalkyl and R2, R3 and R5 are as defined above; and with the proviso that if R2 is unsubstituted or substituted oxoindolyl, then R1 is amino that is unsubstituted or monosubstituted with alkyl or cycloalkyl and R3, R4 and R5 are as defined above; or a tautomer thereof or an N-oxide thereof, or a salt, a hydrate or solvate thereof. |