http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2376894-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a9e6421e9257148abad101e1ce6c162 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4725 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-473 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4725 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-14 |
| filingDate | 2006-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2012-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c89e7293a314d9666a48b75576a7f61c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8315a7e232ade03aa177e5028d955351 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3dc4d38fb26b4b81e35ced143ba8d429 |
| publicationDate | 2012-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2376894-T3 |
| titleOfInvention | Isoquinoline and benzo (H) isoquinoline derivatives, their preparation and their use in therapeutics as histamine H3 receptor antagonists |
| abstract | Compound of formula I ** Formula ** in which: represents an unsaturated carbocycle with double bonds, optionally substituted with one or two substituents independently selected from each other, between a halogen atom, a hydroxy, a nitro, cyano, perhaloalkyl C1 group -2, C1-5 alkyl or a phenyl; l can take a value from 0 to 4; m can take a value from 0 to 3; n can take a value from 0 to 6; - (C) l-, - (C) m- and - (C) n- represent, independently of each other, an alkylidene group -Cx-z-, optionally substituted with 1 to 4 substituents chosen from a halogen atom, a hydroxy, nitro, cyano, amino, perhalogen C1-2 alkyl, C1-3 alkyl or a phenyl group; and also when l, m and / or n take the value 0, - (C) 0 represents a link; R1 represents * a hydrogen atom, * a C1-3 alkyl group, * a C1-6 alkylcarbonyl, * a C1-6 alkoxycarbonyl, each may be substituted with a halogen atom, a hydroxy group, C1-3 alkoxy, nitro, cyano, amino, an aryl; * a C1-3-aryl alkyl group, * a monocyclic heteroaryl, * an aryl; the aryl and heteroaryl groups being optionally substituted with 1 to 4 substituents selected from a halogen atom, a hydroxy, nitro, cyano, amino, C1-3 monoalkylamino, C2-6 dialkylamino, C1-3 alkyl, perhalogen C1-2 alkyl groups, halogen C1-3alkyl, C1-3alkoxy or a C1-3alkylidenedioxy group; R2 represents * a C1-6 alkyl group or a C3-8 cycloalkyl group, each optionally substituted with 1 to 4 substituents chosen from a halogen atom, a hydroxy, nitro, cyano, amino, C1-3 monoalkylamino, dialkylamino group C2-6, perhalogen C1-2 alkyl, halogen C1-3 alkyl, C1-3 alkoxy, C3-6 cycloalkyl, a monocyclic heteroaryl, a bicyclic heteroaryl, an aryl group, itself optionally substituted with 1 to 4 substituents chosen from an atom of halogen, a hydroxy group, nitro, cyano, amino, C1-3 monoalkylamino, C2-6 dialkylamino, C1-3 alkyl, perhalogen C1-2 alkyl, halogen C1-3 alkyl, C1-3 alkoxy or a C1-3 alkylidenedioxy group, in base form or salt addition to an acid, as well as in the state of hydrate or solvate. |
| priorityDate | 2005-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 150.