abstract |
Pharmaceutical composition comprising the compounds of formula 1: in which: M is Gd3 + or Lu3 +; each X is independently selected from the group consisting of OH -, AcO -, Cl-, Br-, I-, F-, H2PO4-, ClO-, ClO2-, ClO3-, ClO4-, HCO3-, HSO4-, NO3-, N3-, CN -, SCN- and OCN-; R4 and R7 are C3H6OH; R5 and R6 are C2H5; R3 and R8 are CH3; R1 and R2 are H, each x is independently selected from the group consisting of 2, 3, 4, 5 and 6; and a pharmaceutically acceptable carrier, wherein each x is 3 in at least 98.4% of the compounds of formula 1 in the pharmaceutical composition. |