abstract |
A bicyclo ester derivative represented by the following general formula (1): wherein R1 is a substituted or unsubstituted C1 to C6 alkyl group, a substituted or unsubstituted C3 to C6 cycloalkyl group, a tetrahydropyranyl group, a substituted arylmethyl group or unsubstituted, a substituted or unsubstituted arylethyl group, a substituted or unsubstituted aromatic hydrocarbon group, a substituted or unsubstituted aromatic heterocyclic ring, or a substituted or unsubstituted aliphatic heterocyclic ring; X is CH2, CHF, CF2, CHOH, S, or O; and n is 1, 2 or 3, or a pharmaceutically acceptable salt thereof. |