| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c22c6d06e5563aee18cc3c610cfa6180 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-20022
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-20032
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-08 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-025
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2002-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2011-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2bd013de7b3e90abe494c318ad0d6632
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4c45af64b6b4734a4ba51e00f785df4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d01371038111c728cc804bf6b2982a4b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98360551c668ff8d16df14dbbd265518
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9bd253ea19874df24187a06b86c19f4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a91e4c7ad91d192383d3328c63b2292
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63c31636bf0dcab1dd480b76bdcca45c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe4c76f1056d05971d51cf9a05ccf9ac
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6c5531e93ac20b5815f4620f66e55d2 |
| publicationDate |
2011-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2371239-T3 |
| titleOfInvention |
PEPTIDES FOR THE TREATMENT OF CANCER ASSOCIATED WITH THE HUMAN PAPILOMA VIRUS (HPV) AND OTHER EPITELIAL TUMORS. |
| abstract |
Peptides useful for the treatment of tumors of epithelial origin and especially those associated with oncogenic types of Papillomavirus (HPV). Identification of peptides whose structure allows the blocking of the phosphorylation domain by Casein Kinase II (CKII) by direct interaction with said site. In the present invention, eleven peptides of different cyclic structure and amino acid sequence are shown, which inhibit the phosphorylation site by CKII in vitro, produce cytotoxicity in human cervical carcinoma cells transformed by HPV-16 (CaSki) and also increase the sensitivity of these cells to the cytostatic effect of Interferon (IFN). The invention also relates to the use of these peptides conjugated or fused to other peptides and chemical compounds of intracellular penetration as well as to the use of mimetic molecules of both peptide and chemical origin. |
| priorityDate |
2001-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |