http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2371170-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2d3599fb8f8f479dba95ca9bb504884 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-381 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-405 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-695 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2005-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0d00aba533dcf03cc9e4893270d63de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_edc10b04822c920f328361a2b1b275cc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_131f78fe2d3d98ef99370a2f81f6f829 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1ca0989bffb8fac55228ff691ebd74a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6653cc8b2989fefb374f5c0061f580a3 |
| publicationDate | 2011-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2371170-T3 |
| titleOfInvention | BENZOFURAN DERIVATIVES SELECTIVE COMMOMODULATORS OF ANDROGEN RECEPTORS (MSRA). |
| abstract | A compound of formula (I) X is O; R4 is selected from the group consisting of hydrogen, halogen, lower alkyl, lower alkenyl, lower alkynyl and cyano; wherein the lower alkyl, lower alkenyl or lower alkynyl is optionally substituted on the terminal carbon atom with -Si (lower alkyl) 3; a is an integer from 0 to 4; R5 is selected from the group consisting of halogen, hydroxy, carboxy, lower alkyl, halogen substituted lower alkyl, lower alkoxy, halogen substituted lower alkoxy, cyano, nitro, amino, lower alkylamino, di (lower alkyl) amino, - C (O) - (lower alkyl), -C (O) - (lower alkoxy), -C (O) -N (RA) 2, - -S (O) 0-2- (lower alkyl), -SO2 -N (RA) 2, -N (RA) -C (O) - (lower alkyl), -N (RA) -C (O) - (lower alkyl substituted with halogen) and aryl; wherein each RA is independently selected from hydrogen or lower alkyl; wherein the aryl is optionally substituted with one or more substituents independently selected from halogen, hydroxy, carboxy, lower alkyl, halogen substituted lower alkyl, lower alkoxy, halogen substituted lower alkoxy, cyano, nitro, amino, lower alkylamino or di (lower alkyl) amino; b is an integer from 0 to 1; c is an integer from 0 to 1; R7 is selected from the group consisting of hydrogen, lower alkyl and -Si (lower alkyl) 3; R2 is - (CH2) 1-4-Z-R6; R3 is selected from the group consisting of lower alkyl, lower alkyl substituted with halogen and - (CH2) 1-4- Z-R6; wherein each Z is independently selected from the group consisting of -S (O) 0-2-, -O- and -O-C (O) -; wherein each R6 is independently selected from the group consisting of lower alkyl, lower alkyl substituted by halogen, lower alkenyl, aryl, aralkyl, biphenyl, cycloalkyl, cycloalkyl- (lower alkyl), heteroaryl and (lower alkyl); wherein the cycloalkyl, aryl or heteroaryl group, alone or as part of a substituent group is optionally substituted with one or more substituents independently selected from halogen, hydroxy, carboxy, lower alkyl, halogen substituted lower alkyl, lower alkoxy, cyano, nitro, amino, lower alkylamino, di (lower alkyl) amino, -S (O) 0-2- (lower alkyl) and -SO2- N (RA) 2; wherein "lower" refers to a carbon chain composition of 1-4 carbon atoms with the proviso that when Z is O then R6 is different from lower alkenyl; with the additional condition that when R4 is hydrogen, b is 0, c is 0, R7 is hydrogen and R2 is hydrogen, then R3 is different from CH2-O-phenyl, in which the phenyl is optionally substituted with one to two substituents independently selected from lower alkyl and carboxy; or a pharmaceutically acceptable salt thereof. |
| priorityDate | 2004-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 484.