| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42e94091a4fc81b8d0237117707cc7ee |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70596
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-71
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-485 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57419
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 |
| filingDate |
2006-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2011-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d598ffe92de0f18f72cec452a657433e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7e15ec48453923c1037ce7811b4fad1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4410fe833d30d86edea7cfcd48b70ef4 |
| publicationDate |
2011-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2370054-T3 |
| titleOfInvention |
BIOMARKERS AND PROCEDURES TO DETERMINE THE SENSITIVITY TO MODULATORS OF THE RECEIVER OF THE EPIDERMAL GROWTH FACTOR. |
| abstract |
An in vitro procedure for predicting the likelihood of a mammal responding therapeutically to a colorectal cancer treatment method, comprising administering an EGFR modulator that inhibits EGF binding to EGFR or EGFR kinase activity, in which the procedure it comprises measuring the mRNA expression level of both the epirregulin and anfirregulin biomarkers in a biological sample of said mammal, in which a high expression level of said biomarkers with respect to a predetermined level indicates an increased probability that the mammal responds therapeutically to said colorectal cancer treatment procedure. |
| priorityDate |
2005-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |