http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2369389-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4725 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 |
| filingDate | 2006-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36604fd0b1776be17ce826816302c7d6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ffc26279c54a72b402f2c72be7c9ed7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5ae991159634994e2322ca95faae1f5 |
| publicationDate | 2011-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2369389-T3 |
| titleOfInvention | 1H-PIRAZOL-4-CARBOXAMIDES, ITS PREPARATION AND ITS USE AS INHIBITORS OF 11-BETA- HYDROXIESTEROID DEHYDROGENASE. |
| abstract | A compound of the formula I: ** Formula ** in which one of R1 and R2 is hydrogen or unsubstituted alkyl and the other is unsubstituted lower alkyl or (CH2) pY, in which Y is a mono- cycloalkyl ring , bi- or tricyclic, saturated, partially unsaturated or unsaturated, 5 to 10 links, substituted or unsubstituted and p is the number 0 or 1, and in which the substituents of Y are lower alkyl, lower alkoxy, hydroxy, hydroxy- alkyl, alkyl-phenyl, phenyl-alkyl, pyridine or halogen, or R1 and R2, together with the N atom to which they are attached, form a substituted or unsubstituted Z ring, wherein Z is a saturated heterocyclic ring, partially unsaturated or unsaturated, substituted or unsubstituted, monocyclic of 5 to 7 links or bicyclic of 7 to 10 links, which contains the N atom to which R1 and R2 are attached, and optionally another heteroatom chosen from N, O and S, wherein the substituted heterocyclic ring is mono- or disubstituted by alkyl in ferior, hydroxy, hydroxy-alkyl, alkyl-phenyl, phenyl-alkyl, pyridine or halogen; R3 is an aromatic ring system selected from the group consisting of [2,2 '] bitiophenyl, 1-methyl-indole, 2,3-dihydrobenzo [1,4] dioxin, benzo [1,3] dioxol , benzo [b] thiophene, benzothiophene, dibenzofuran, furan, naphthalene, phenyl, biphenyl, quinoline, thiantrene and thiophene, wherein said aromatic ring may be unsubstituted or substituted by one or more amino groups, cyano, formyl, halo, hydroxy, hydroxymethyl, lower acyl, lower acyl-amino, lower alkoxy, lower alkoxy-carbonyl, 2- (lower alkoxy-carbonyl) -ethyl, lower alkyl, lower alkylthio, nitro, trifluoromethoxy or trifluoromethyl, said phenyl ring may be further substituted by phenoxy or benzyloxy, R4 is lower alkyl; and pharmaceutically acceptable salts thereof, wherein "lower alkyl" is a branched or unbranched acyclic saturated C1-C4 hydrocarbyl radical; and wherein "alkyl" is a branched or unbranched C1-C10 saturated hydrocarbyl radical. |
| priorityDate | 2005-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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