http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2368203-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a48132fcc2f50a7107021f911f887cb |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D275-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D275-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D261-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-423 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-416 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4162 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D261-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D275-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D275-06 |
| filingDate | 2005-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b0f84b30aaa494695ce94c9e242d3d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fcb39b4caabf6e81d7aa55e8f7edc07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55cde34f0bb01da6340bedebef416c1d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6df9ee1ea4de6a18e00bfe7980032f8c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a29eea1751a407c5b5c8fb5d629dbd6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d331e46ab3accb7dfbf5232cdbee78ee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9368a8073638632883dcfced04259a47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e80384df543b4a93594b26c0641d3de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3170e61892f7aa425e74fc601dc10863 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b4a825ad9c8db7e895d3d7e58187b8a |
| publicationDate | 2011-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2368203-T3 |
| titleOfInvention | INDAZOLES, BENCISOXAZOLES AND BENCISOTIAZOLES AND ITS USE AS A STROGEN AGENTS. |
| abstract | A compound of formula (I) or an acid addition salt or a stereoisomeric form thereof, in which: - R1 is hydrogen or a (C1-C6) alkyl, cycloalkyl (C3-C6), trifluoromethyl, -N = CR5R6, - SO2NR7R8, phenyl, phenylalkyl (C1-C3) or alkyl (C1-C3) substituted by a saturated heterocyclic radical, in which the phenyl is unsubstituted or substituted by at least one substituent selected from the group consisting of a hydroxyl , a halogen, a nitro, a cyano, a (C1-C3) alkyl, a (C1-C3) alkoxy, and a trifluoromethyl; R1 can also be a salt; - R2 and R3 are each independently hydrogen or a hydroxyl, halogen, nitro, cyano, (C1-C6) alkyl, (C3-C6) cycloalkyl, (C1-C6) alkoxy, trifluoromethyl, a group -NR7R8, - CONR7R8, -COR9 or -CO2R9; R2 may also be a saturated or unsaturated phenyl or heterocycle, in which the phenyl is unsubstituted or substituted by at least one substituent selected from the group consisting of a hydroxyl, a halogen, a nitro, a cyano, a (C1) alkyl -C3), a (C1-C3) alkoxy, a trifluoromethyl and a saturated heterocyclic radical; - X is O, S, SO, SO2 or NR4; - R4 is hydrogen or a (C1-C6) alkyl, cycloalkyl (C3-C6), phenyl, phenylalkyl (C1-C3), (C1-C3) alkyl substituted by a saturated heterocyclic radical, a group -COR7, -CO2R7 or -SO2NR7R8, in which the phenyl is unsubstituted or substituted by at least one substituent selected from the group consisting of a hydroxyl, a halogen, a nitro, a cyano, a (C1-C3) alkyl, a (C1-C3) alkoxy ), a trifluoromethyl, a (C1-C3) phenylalkyl and a (C1-C3) phenylalkoxy; - Y is a direct link, O, S, SO, SO2, NR4, CO, - (CR10R11) n- or -R10C = CR11-; - R5, R6, R7 and R8 are each independently hydrogen or a (C1-C6) alkyl or cycloalkyl (C3-C6) group; - R9 is hydrogen, a (C1-C6) alkyl, a phenyl or a saturated or unsaturated heterocyclic radical, in which the phenyl is unsubstituted or substituted by at least one substituent selected from the group consisting of a hydroxyl, a halogen, a nitro, a cyano, a (C1-C3) alkyl, a (C1-C3) alkoxy, a trifluoromethyl and a saturated heterocyclic radical; - R10 and R11 are each independently hydrogen or a cyano, (C1-C6) alkyl, -CO-phenyl, -CO (unsaturated heterocyclic radical) or a group -CONR7R8, in which the phenyl is unsubstituted or substituted by at least one substituent selected from the group consisting of a hydroxyl, a halogen, a nitro, a cyano, a (C1-C3) alkyl, a (C1-C3) alkoxy, and a trifluoromethyl; - n is 1 or 2; - A is a cycloalkyl (C3-C15), a cycloalkene (C3-C15), in which the cycloalkyl or cycloalkene is unsubstituted or substituted by at least one (C1-C6) alkyl; provided that: 1 / when X is NR4 where R4 is H or (C1-C6) alkyl and R1O is 6-OCH3, then Y is not CO; 2 / when X is O, R1O is 6-OH or 6-OCH3, Y is a direct bond and A is cyclopentyl, then (R2, R3) or (R3, R2) is different from (H, Cl) in Position 4 ,5; 3 / the compound is not |
| priorityDate | 2004-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 359.