http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2366390-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_44e0905262f429c7590b40df8448c0c5 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C213-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C219-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C215-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C217-56 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C219-22 |
| filingDate | 2007-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f12d7f6e500be4f0ccb938c8225fe22 |
| publicationDate | 2011-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2366390-T3 |
| titleOfInvention | PREPARATION OF 3- [(1R, 2R) -3- (DIMETHYLAMINE) -1-ETIL-2-METHYLPROPIL] -PHENOL. |
| abstract | Process for preparing a compound of formula (VIII), or an acid addition salt thereof, characterized by the steps of: a) acylation of a compound of formula (VI) where R represents (C 1-6) alkyl, cycloalkyl ( C3-8), alkyl (C1 6) carbonyl, tetrahydropyranyl or (C1-3) alkyl substituted with phenyl or naphthyl (with the proviso that R = methyl is excluded) with an acylating agent; b) hydrogenolysis of the compound (VII) thus obtained acyl using a suitable catalyst, in a solvent inert to the reaction, in the presence of hydrogen, whereby product VIII is obtained with R 1 = R or H; c) optionally, deprotection of the group R1 in formula VIII in case of R1-H; and d) optionally, conversion of the deprotected product obtained into an acid addition salt. |
| priorityDate | 2006-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 147.