http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2366269-T3

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_efe62eb5da2447abb87721cd79e86d11
classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-35
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54393
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-00
filingDate 2008-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2011-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0b6e64c189a1e1a8a88a4f2d537efc1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eddd1f9d16ef063a29c324117fc49b62
publicationDate 2011-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2366269-T3
titleOfInvention DETECTION OF TUMOR HEMOCITOBLASTS AND TUMOR CELLS IN THE EPITELIO-MESENQUIMA TRANSITION IN BODY FLUIDS OF CANCER PATIENTS.
abstract Solid phase procedure for isolation, enrichment and / or detection to isolate, enrich and / or detect tumor hemocytoblasts and / or tumor cells in epithelial-mesenchymal transition as predetermined cells from a sample of body fluid containing said predetermined cells for at least one of the group that includes staging, prognosis and therapeutic guidance. said method comprising a selection step for the selection or enrichment of said predetermined cells from the sample in which the sample is contacted with a solid surface for preferential binding of said predetermined cells to the solid surface and subsequently the sample is removed from the solid surface in a washing step, characterized in that, in said selection stage for the selection or preferential enrichment in tumor cells, the sample contains a polyol for at least one of the sample coming into contact with the solid surface and the washing step and in a detection stage that detects in said cells, which have preferably been selected or enriched by said selection step, the presence or absence of expression of at least one marker associated with at least one of the group comprising hemocytoblasts Tumor and tumor cells in epithelial-mesenchymal transition.
priorityDate 2007-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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