http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2366268-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2008-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d42f014dd782a8548c123d1bb62b4e01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_879a8a0558f0721d3cd5f05361dafa88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_345e455fb444105bc6dfdb74ba5fb78f |
| publicationDate | 2011-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2366268-T3 |
| titleOfInvention | DERIVATIVES OF PIRAZOLOL (3,4-d) -PIRIMIDINE AS AN ANTIPROLIFERATIVE AGENT. |
| abstract | A compound that is one according to Formula (I), wherein R is lower alkyl; Ring A is selected from the group consisting of: heteroaryl; heteroaryl substituted by 1 to 5 substituents independently selected from the group consisting of lower alkyl; halogen; hydroxyl; lower alkoxy; lower alkoxy substituted by hydroxyl or lower alkoxy; and cyano; phenyl; and phenyl substituted by 1 to 4 substituents independently selected from the group consisting of lower alkyl; halogen; hydroxyl; lower alkoxy; lower alkoxy substituted by hydroxyl or lower alkoxy; and cyano; Ring B is selected from the group consisting of: heteroaryl; heteroaryl substituted by 1 to 5 substituents selected from the group consisting of lower alkyl; fluorinated alkyl; alkyl substituted with aryl; hydroxyl; lower alkoxy; lower alkoxy substituted by hydroxyl or lower alkoxy; halogen; and -NR 1 R 2; phenyl; and phenyl substituted by 1 to 5 substituents selected from the group consisting of lower alkyl; fluorinated alkyl; alkyl substituted with aryl; hydroxyl; lower alkoxy; lower alkoxy substituted by hydroxyl or lower alkoxy; halogen; cyano; and -NR 1 R 2; R 1 and R 2 are independently selected from each other from the group consisting of hydrogen; lower alkyl; and lower alkyl substituted with hydroxyl or lower alkoxy; and R 1 and R 2, together with N, can form a 5- or 6-membered heterocyclic ring; and L is selected from the group consisting of a link, -OCH2-, -CH2O-, - NHCO-, -CONH-, -O-, -OCH2CH2-, -CH2OCH2, -CH2CH2O-, -CF = CH- , -CH = CF-, -NH-, -NHCH2-, -CH2NH-, -SCH2-, - CH2S-, -SOCH2-, -CH2SO-, -SO2CH2-, -CH2SO2-, -S-, -CH = CH-, and lower alkyl; and in which the term "lower" refers to a group having 1 to 6 carbon atoms; with the proviso that, when L is a bond, ring B is an azol substituted by 1 to 4 substituents selected from the group consisting of: lower alkyl; fluorinated alkyl; alkyl substituted with aryl; hydroxyl; lower alkoxy; lower alkoxy substituted with hydroxyl or lower alkoxy; halogen; cyano; and -NR 1 R 2; or a pharmaceutically acceptable salt or ester of a compound according to Formula (I) ,. |
| priorityDate | 2007-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 231.