http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2366001-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37f4922dfb7777b019e504b885211b8e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d78c2037dd3f1767290707556ac65151 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0613 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06078 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-061 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-065 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-062 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-075 |
| filingDate | 2008-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f90f6010c2c00392dd9332da55afe9c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5939fe393275d470cae93b73b26eceb7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_468cc2cef4f91de8c71f161bb6ec45c5 |
| publicationDate | 2011-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2366001-T3 |
| titleOfInvention | SYNTHESIS PROCEDURE FOR PEPTIDES WITHOUT SOLVENT. |
| abstract | Synthesis process of a compound of the following formula (I): in which: - n is an integer greater than or equal to 1, preferably between 1 and 100, more preferably between 1 and 50, more preferably still equal to 1 or 2; - Rb and each Rn independently represent each other a hydrogen atom, an aryl group (C1 to C6 alkyl) or a C1 to C6 alkyl group substituted or not substituted by an aryl group, -COOH, -COO- (C1 alkyl to C6), -CONH2, -SH, heteroaryl, -NH2, -NHC (NH) (NH2), -S- (C1 to C6 alkyl), -OH or phenol, whose functions NH2, NH, COOH, SH and OH of these groups are eventually protected by one or more identical or different O-protector or N-protector groups, and different from Ra; - Ra represents an N-protective group; - Rc represents a -ORd group in which Rd represents a C1 to C6 alkyl group or a -NReRf group in which Re and Rf independently represent each other an N-protective group, characterized in that it comprises a step (a) consisting in reacting in the presence of a base and without solvent the compound of the following formula (II): in which Ra and Rb are as defined above, with the compound of the following formula (III): in which n, Rn and Rc are as defined above, as well as their pharmaceutically acceptable salts, preferably chlorides, acetates and trifluoroacetates. |
| priorityDate | 2007-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 76.