| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d7cb3ffe72a0132b19d52f416ddb2d0a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7da5c8e8c3e8261efe7e698c7198681b |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7008 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H5-10 |
| filingDate |
2010-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2012-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1216324d7904d8a0752c3da270640a9e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_252d97085524e9fc3bc76a75ed6adb2c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01f39c0869a510797e8cb7d2cc9011ea
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a26f22a38c1ed22685d087099e5923d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c2a2575b9aed385403d1c6f36c53cd2 |
| publicationDate |
2012-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2365314-B1 |
| titleOfInvention |
SULFURIZED DERIVATIVES OF N-ACETYLHEXOSAMINS AND ITS USE AS INHIBITORS OF THE TUMOR CELL DIVISION. |
| abstract |
Sulfur derivatives of N-acetylhexosamines and their use as inhibitors of tumor cell division. # The present invention describes a series of thioglycosides and their oxidized derivatives sulfoxide and sulfone, which confer greater solubility in aqueous media, and their use as antitumor agents, mainly against glioma and lung adenocarcinoma cell lines. The new thioderivatives are resistant to hydrolysis catalyzed by N-acetylhexosaminidases enzymes and reduce the content of gangliosides in tumor cells. The invention also relates to a method of obtaining these compounds and their use for the manufacture of a medicament for the treatment of tumors. |
| priorityDate |
2010-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |