Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d7cb3ffe72a0132b19d52f416ddb2d0a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7da5c8e8c3e8261efe7e698c7198681b |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7008 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H5-10 |
filingDate |
2010-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c2a2575b9aed385403d1c6f36c53cd2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1216324d7904d8a0752c3da270640a9e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ceae4662b606ade8bf022e01d6df6a21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01f39c0869a510797e8cb7d2cc9011ea http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a26f22a38c1ed22685d087099e5923d |
publicationDate |
2011-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
ES-2365314-A1 |
titleOfInvention |
SULFURIZED DERIVATIVES OF N-ACETYLHEXOSAMINS AND ITS USE AS INHIBITORS OF THE TUMOR CELL DIVISION. |
abstract |
Sulfur derivatives ofnN-acetylhexosamines and their use as inhibitors ofndivision of tumor cells.n n n The present invention describes a series ofnthioglycosides and their oxidized sulfoxide and sulfone derivatives, whichnconfer greater solubility in aqueous media, and its use asnantitumor drugs, mainly against glioma cell lines andnlung adenocarcinoma. The new thioderivatives are resistant tonenzyme catalyzed hydrolysisnN-acetylhexosaminidases and reduce the content ofngangliosides in tumor cells. The invention also relates tona procedure for obtaining these compounds and their use fornmanufacture of a medicament for the treatment of tumors. |
priorityDate |
2010-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |