| abstract |
A preparation of novel chemically modified erythropoietin stimulating protein (NESP), optionally in a pharmaceutically acceptable diluent, carrier or adjuvant, wherein said NESP is chemically modified with a chemical compound selected from the group consisting of dextran, poly (N-vinyl pyrrolidone) , polyethylene glycols, propylene glycol homopolymers, polypropylene oxide / ethylene oxide copolymers, polyoxyethylated polyols and polyvinyl alcohols, and wherein the preparation is at least 90% polymer conjugate: protein, and at most 10% protein that does not He has reacted. |