http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2362656-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D261-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D285-135 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D285-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D285-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D261-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D285-135 |
| filingDate | 2003-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_932c400c6e53d69e798298402aef9ee6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_871ad74f4480405fcc93f29c7079c8b0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2222c6428ef41eeb16ab3a9feddb7598 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eaf64cdfe4310adf7df34d4d07bcc6ac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c39cb88df0b455bdd05dbda859681a3d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efea3bf7f2f21ebdd42629d44f5b9594 |
| publicationDate | 2011-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2362656-T3 |
| titleOfInvention | ARILCICLOPROPILACETAMIDES REPLACED AS GLUCOQUINASE ACTIVATORS. |
| abstract | A compound of the formula ** Formula ** in which M is hydrogen, halo, C 1-7 alkyl, or C 1-7 perfluoroalkyl; Rx and Ry are hydrogen, halo or methyl; R1 is hydrogen, halo, nitro, cyano or C1-7 perfluoroalkyl; R2 is halo, C1-7 alkyl sulfonyl, R10 - [(CH2) and -W] z- or R13- (CH2) t-U-; W is oxygen, sulfur, -SO- or -SO2-; R10 is a heteroaromatic ring, connected by a ring carbon atom, containing 5 to 6 ring members with 1 to 2 heteroatoms selected from the group consisting of oxygen, sulfur or nitrogen, or aryl containing 6 to 10 atoms carbon ring, or aryl containing 6 ring carbon atoms condensed with a heteroaromatic ring containing 5 or 6 ring atoms with 1 or 2 ring heteroatoms, which are selected from the group consisting of nitrogen, oxygen or sulfur , or a saturated 5 or 6 membered cycloheteroalkyl ring containing 1 to 2 heteroatoms selected from the group consisting of nitrogen, oxygen and sulfur, or a cycloalkyl ring having 5 or 6 carbon atoms, or -NR11R12, R11 and R12 being independently hydrogen or C1-7 alkyl; and is independently 0, 1, 2, 3 or 4; z is independently 0 or 1; U is -NHCO-, -CONH-, -NHSO2 or -SO2NH-; R13 has the same meaning as R10,, and perfluoroalkyl C1-7, C1-7 alkyl, C1-7 alkoxycarbonyl or -NR14R15, R14 and R15 are independently hydrogen or C1-7 alkyl or together with the nitrogen atom at which are attached form a 5- or 6-membered heteroaromatic ring containing 1 to 3 heteroatoms selected from sulfur, oxygen or nitrogen; or a 5- or 6-membered heterocycloalkyl ring containing 1 to 2 heteroatoms selected from the group consisting of oxygen, sulfur and nitrogen; t is an integer that is 0, 1, 2, 3 or 4; R3 is C1-7 alkyl or haloalkyl having 2 to 6 carbon atoms, or arylalkyl or - (CH2) sV, where V is a 3 to 8 member ring that is cycloalkyl, cycloalkenyl or heterocycloalkyl having 3 to 8 atoms of carbon and a heteroatom selected from oxygen and sulfur; s is, independently, 0, 1 or 2; R4 is selected from thiazolyl, imidazolyl, oxazolyl, thiadiazolyl, pyridinyl, pyrimidinyl, pyrazinyl, pyridazinyl or triazinyl, which are unsubstituted, monosubstituted or disubstituted with a substituent selected from the group consisting of C1-7 alkyl, halo or - (CH2) n-COOR21; n is 0, 1, 2, 3 or 4; and R21 is hydrogen or C1-7 alkyl, and its pharmaceutically acceptable salts. |
| priorityDate | 2003-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 669.