http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2361632-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b8726f713a6d86892687edccfa03d886 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 |
| filingDate | 2007-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_396920016c04f75286030c8d391b6820 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_016c544b2f8a51bb46efa70fb00d1ad3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c896a7e1ccb8877454782d7298ef686 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00ac42e3a6dcdbb14f8ae33202bdfe86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eade9de3279ae8766324643c46a615c9 |
| publicationDate | 2011-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2361632-T3 |
| titleOfInvention | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CHANNEL ACTIVATING PROTEASES. |
| abstract | A compound of formula (1): ** Formula ** and pharmaceutically acceptable salts, hydrates, solvates and stereoisomers thereof, wherein J is a condensed monocyclic or carbocyclic ring of 5 to 12 members, an aryl ring, heteroaryl or heterocyclic containing N, O and / or S; R1 is - (CR2) 1-NR2, - (CR2) 1-NRC (= NR) -NR2, - (CR2) 1-C (= NR) -NR2 or a 5- to 7-membered non-aromatic heterocyclic ring containing nitrogen; W-R2 is a substituent at any position of ring A; W is -O (CR2) k-, -S (CR2) k-, -S (O) (CR2) k-, -SO2 (CR2) k- or -OC (O) (CR2) k-; R2 is C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, R6, -CR9 = CR9-R6 or wherein the E ring is an optionally substituted 5 to 7 membered fused monocyclic or carbocyclic or heterocyclic ring; or W-R2 together form C1-6 alkyl, 5-7 membered aryl or -OC (O) NR7R8-, R3 is R6; R4 and R5 are independently H, C1-6 alkyl, OH or C1-6 alkoxy; R7 and R8 are independently H, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl or - (CR2) 1-R6; or R7 and R8 can form together with N an optionally substituted 5 to 7 membered monocyclic or heterocyclic ring; R9 is H or C1-6 alkyl; R10 is halogen, C1-6 alkyl, C1-6 alkoxy, OR11 or - (CR2) 1-R11; R6, R11 and X are independently a carbocyclic ring, an optionally substituted 5- to 7-membered heterocyclic, aryl or heteroaryl ring; or R11 is H or C1-6 alkyl; each R is H or C1-6 alkyl, C2-6 alkenyl or C2-6 alkynyl, in which a carbon may be optionally substituted or replaced by NR, O or S; i is 0 to 1; k and 1 are independently 0 to 6; m and n are independently 1 to 6; and p is 0 to 3. |
| priorityDate | 2006-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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