| abstract |
A hair growth promoting agent comprising a cyclosporine analog substituted in position 3 represented by formula 1, as an active ingredient wherein: MeBmt represents N-methyl- (4R) -4 - [(E) -2-butenyl ] -4-methyl-L-threonine; Abu represents L-aminobutyric acid; MeLeu represents N-methyl-L-leucine; Va represents L-valine; Ala represents L-alanine; DAla represents D-alanine; MeVal represents N-methyl-L-valine; wherein X is [D-2-ethylthio-sarcosine], [D-2-propylthio-sarcosine], [D-2-isopropylthio-sarcosine], [D-2-allylthio sarcosine], [D-2-benzylthio- sarcosine], [D-2- (4-nitrophenyl) thio-sarcosine] or [D-2- (dimethylthiocarbamil) dithio-sarcosine]. |