http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2358351-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bb4fc267a1fcbba804230f5c3bf18e58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_71499ee5cbc2e0ef0934e4f106318743 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-06 |
| filingDate | 2006-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_151ed6dbb036deb5814239ec7481847f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b1bea3600872309a927fba8726f42fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5fbc53642ffbef6084cfdaf83f4d8ff8 |
| publicationDate | 2011-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2358351-T3 |
| titleOfInvention | ADENOSINE RECEIVER AGONISTS A1. |
| abstract | Compound of formula I: ** Formula ** in which: R is hydrogen; R1 is cycloalkyl of 3-6 carbon atoms; R2 is alkyl having up to 20 carbon atoms and which is substituted with -SO3H, cycloalkyl having up to 20 carbon atoms and which is substituted with -SO3H, aryl having up to 20 carbon atoms and which is substituted with -SO3H; heteroaryl having up to 15 carbon atoms and which is substituted with -SO3H, or heterocyclyl having up to 40 carbon atoms and which is substituted with -SO3H; R3 is -CH2OH; R4 and R5 are independently hydrogen or alkyl having up to 6 carbon atoms; and Y is an optionally substituted covalent or alkylene bond having up to 20 carbon atoms; or a pharmaceutically acceptable salt thereof, wherein substituted alkylene refers to (i) an alkylene group having from 1 to 5 substituents selected from the group consisting of alkyl, alkenyl, alkynyl, alkoxy, cycloalkyl, cycloalkenyl, acyl, acylamino, acyloxy, amino, aminocarbonyl, alkoxycarbonylamino, azido, cyano, halogen, hydroxyl, keto, thiocarbonyl, carboxyl, carboxyalkyl, arylthio, heteroarylthio, heterocyclyl, thiol, alkylthio, aryl, aryloxy, heteroaryl, aminosulfonyloyl, aminocarbonylamino, heteroxylamino, heteroxylamino, heteroxylamino, amino heterocyclooxy, hydroxyamino, alkoxyamino, nitro, phosphate, -SO-alkyl, -SO-aryl, -SO-heteroaryl, -SO2-alkyl, -SO2-aryl and -SO2-heteroaryl, in which all substituents are optionally further substituted with between 1 and 3 substituents selected from alkyl, carboxyl, carboxyalkyl, aminocarbonyl, hydroxyl, alkoxy, halogen, CF3, amino, substituted amino, cyano and -S (O) nR, in which R is alkyl, aryl or heteroaryl and n is 0, 1 or 2, (ii) an alkylene group that is interrupted by 1 to 5 atoms or groups independently selected from oxygen, sulfur and -NRa-, in which Ra is selected from hydrogen, optionally substituted alkyl, cycloalkyl, cycloalkenyl, aryl, heteroaryl and heterocyclyl, or groups selected from carbonyl, carboxy ester, carboxyamide and sulfonyl, or (iii) an alkylene group having 1 to 5 substituents as defined previously in (i) and is interrupted by between 1 and 20 atoms as defined above in (ii). |
| priorityDate | 2005-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 688.