abstract |
A compound of the general formula: ** Formula ** where, - R 1 is a mono- or bicycloalkylalkyl group; - R2 is selected from linear or branched C1-C5 alkyl which may be optionally substituted with -OH, C1-C5 alkoxy, NH2-, N (Ra) 2-, NHRa-, CN-, CF3, halogen, piperidino, morpholino, pyrrolidino, 5H-tetrazolylpropyl, methylcarbamoyl, dimethylcarbamoyl, or ethylmethylcarbamoyl, where Ra is hydrogen or C1-C5 alkyl; - R3, R4, R5, are independently selected at each occurrence from hydrogen, halogen, methyl, hydroxy, methoxy, cyano, or trifluoromethyl; - R6 is hydrogen; - a, b, c, d, x are independently selected at each occurrence between carbon, or nitrogen; or one of its pharmaceutically acceptable salts or solvates. |