http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2357216-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_07addebfc9446dc5a9a77692ebf4dac1 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D489-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D489-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D489-00 |
| filingDate | 2006-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61dcaad3180fe5dec9c22fe29df85670 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_372963e38f548913195f0c6fb15022f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8caca0db4746e71dee015eec61a3b0ad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1261d3d1669049ea20ccac35b658ef5a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3938b2eebb56b036a325974fc7f0dde |
| publicationDate | 2011-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2357216-T3 |
| titleOfInvention | A SYNTHESIS ROUTE OF 14-HYDROXYL-OPIACES THROUGH 1-HALO-THEBAINE OR ANALOGS. |
| abstract | A process in a single flask for the conversion of a composition according to Formula 14 into a composition according to Formula 17, the process comprising: a) heating the composition according to Formula 14 in the presence of at least one acid to form a composition according to Formula 15; wherein R 1 is H, methyl, a benzyl group, an aryl group, an acyl group, an alkoxycarbonyl group, or a tetrahydropyranyl group; R 2 is H, methyl, a benzyl group, an aryl group, an acyl group, a formyl group, a formyl ester, an alkoxycarbonyl group, or an alkylamidocarbonyl group; and X is a halogen; b) oxidizing the composition according to Formula 15 with at least one oxidizing agent to form the composition according to Formula 16; wherein R 3 is H, an alkyl group, an aryl group, and an acyl group. c) reduce the composition according to Formula 16 with at least one reducing agent to form the composition according to Formula 17; wherein the at least one reducing agent includes a reducing agent that is chosen from the group consisting of a combination of pressurized hydrogen and a metal supported catalyst chosen from M / C, wherein M is Pd, Pt, Ru, or Rh and C is carbon. |
| priorityDate | 2005-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 116.