http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2355677-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_709b4a26ef028713f9b302509eb824d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ee602c630e57f59c6cfc1c1634e36064 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1085 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-513 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 1997-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65fe00c9a2f34b386e3d8d8c4f376c49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_189f96a5afff6e971ff2b5b70a81ce53 |
| publicationDate | 2011-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2355677-T3 |
| titleOfInvention | USE OF MUTANT RENTALS FOR GENETIC THERAPY TO PROTECT FROM THE TOXICITY OF RENTAL THERAPEUTIC AGENTS. |
| abstract | THE INVENTION REFERS TO PROCEDURES FOR TREATING NEOPLASIC DISEASES IN WHICH GENETIC THERAPEUTIC TREATMENTS ARE USED IN COMBINATION WITH A CHEMOTHERAPY REGIME. A COMBINATIONAL THERAPY WITH ANTINEOPLASTIC RENTAL AGENTS WILL OPTIMIZE THE SENSITIVITY TOWARDS THE HUMAN TUMORS OF THESE AGENTS USED ONLY OR IN COMBINATION WITH OR 6 -BENZILGUANINE (BG) OR A COMPOUND OR SIMILAR COMPOUNDS. HAMATOPOIETIC CELLS ARE INFECTED WITH A TRANSGEN THAT EXPRESSES A MUTANT AGT PROTEIN THAT DISPLAYS DNA REPAIR ACTIVITY WHILE PROVIDING BG RESISTANCE OR A RELATED COMPOUND. THE INTRODUCTION OF TRANSMITTED HEMATOPOIETIC CELLS POPULATIONS THAT EXPRESS THE AGT MUTANT PROTEIN IN THE PATIENT TOGETHER WITH THE CHEMOTHERAPEUTIC REGIME SUBSTANTIALLY REDUCE THE TRADITIONALLY HONEY SUPPRESSION ASSOCIATED WITH THE ADMINISTRATION OF ADMINISTRATION. |
| priorityDate | 1996-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 493.