http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2354086-T3
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_589b4e7af26cc1f1fd30dee3d5cb9ced |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-974 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-56 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-86 |
filingDate | 2006-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2011-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d79761608925f8d6446041200b7b4a24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4f172f82b27103b9c53e6a4a5f90655 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23270e8b7f2b97e3bc95e33b8d9eb19d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_47b920a47b8f69769dae74a754218916 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e4749565d72b035ba909275dedb0abe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e3a911c4f4a28762b09d1576bf601b8 |
publicationDate | 2011-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2354086-T3 |
titleOfInvention | DETERMINATION OF THROMBIN ACTIVITY IN COMPLETE BLOOD. |
abstract | A method for determining in vitro the activity of thrombin in a biological sample that is a whole blood sample or a plasma sample and in which thrombin generation is measured by the steps of: - contacting a layer of said sample with a thrombin fluorogen substrate and with a known concentration of fluorophore in which said fluorophore is in the range of 1-10% of the amount of fluorescent molecule bound to the thrombin fluorogen substrate, and in which said layer has a thickness within a range of 0.05 to 5 mm and a surface within a range of 10 to 500 mm 2, and in which said sample is introduced into a container containing means that aid dispersion of the sample; - allow thrombin to be generated in said sample; - measuring the fluorescence emitted from the surface of the layer, by the fluorescent group released from the fluorogenic substrate as a result of the enzymatic action of the thrombin generated on said fluorogenic substrate. |
priorityDate | 2005-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 120.