| abstract |
Peptide for use in therapy represented by the general formula I: ** (See formula) ** in which: a is 1 and b is 0; or b is 1 and a is 0; d is 0-8; and z is 1-7; y x is 1, and y q are 1, and p is 0; or p is 1, x and q are 0, and y is 1; and also in which, if R1 is H, then d is 0-8; or if R1 is not H, then d is 0; wherein R1 is the side chain of an amino acid selected from the group consisting of alanine, arginine, asparagine, aspartic acid, cysteine, glutamic acid, glutamine, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, proline, serine , threonine, tryptophan, tyrosine, and valine; wherein R2 is selected from the group consisting of NH2, NHR, NR2, NR3 + H, OH, SH, RO, RS, RSO, RSO2, COR, CSR, COOH, COOR, CONH2, CONHR, CONR2, OCOR, and SCOR, in which R = alkyl, alkenyl, aryl, aralkyl or cycloalkyl; wherein R3 is H or CH3; and in which RX is a hydrophobic group; or a pharmaceutically acceptable salt thereof. |