| abstract |
A substance capable of inducing and / or enhancing the expression of Pax2 selected from the group consisting of a nucleic acid molecule that encodes Pax2 protein, a Pax2 protein, a growth factor, a cytokine, lithium, LIF (leukemia inhibitor factor) , osteopontin, an apoptotic protein and STAT-3 (signal transducer and activator of transcription) for use in the treatment, delay and / or prevention of renal dysfunction / insufficiency in a mammal, in which said dysfunction / Renal insufficiency is chronic renal failure and in which said cytokine is IL-6 or cytokine of type IL-6. |