http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2351662-T3
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c4c517963f93eda4f5adf845a868be23 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C237-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-12 |
filingDate | 2004-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2011-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c19124292681c1b5ef27d1e3e1cd490 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f6fb246c5a3e6a938178a98740160b9 |
publicationDate | 2011-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2351662-T3 |
titleOfInvention | A METHOD FOR THE PREPARATION OF CRYSTAL DEXLOXIGLUMIDE. |
abstract | A method for the preparation of crystalline dexloxiglumide by crystallization of the crude product from a solvent, characterized in that isopropyl ether is used as the solvent and because the crystallization step is performed by adding a microcrystalline dexloxiglumide seed having an average particle size (D50) <= q 20 μm (measurement method performed by laser light diffraction with the Malvern Master Sizer 2000 instrument) to a supersaturated solution of raw dexloxiglumide, in which the seed is added to said supersaturated solution of raw dexloxiglumide which is maintained at a temperature between 35 and 40 ° C, in a ratio of one part of seed material to 40-200 parts of raw product, and in which the dexloxiglumide thus prepared is in the form of crystalline particles having a percentage in volume of less than 15% fine particles having dimensions of less than 10 μm and a value of the average size of particles (D50) between 50 and 130 μm (measurement method performed by laser light diffraction with the Malvern Master Sizer 2000 instrument). |
priorityDate | 2003-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.