http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2350504-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-20 |
| filingDate | 2007-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c15e9b8b5f44d1f23eba096d1017c07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0abd2ff28f9d5280750e89ab0e196ce3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c55066547cf34dce3f7b3d4850bffc9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c616320db2c9d12f9af9947557c1e8d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_169654442a90b80dc3eada674f39b8b0 |
| publicationDate | 2011-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2350504-T3 |
| titleOfInvention | SPIROINDOLINONE DERIVATIVES. |
| abstract | A compound of the formula Y R 7 R 6 R 4 R 5 X N H R 3 N R 2 X is selected from the group consisting of hydrogen, halogen, cyano, nitro, ethynyl, cyclopropyl, methyl, ethyl, isopropyl, methoxy, and vinyl; Y is hydrogen or fluorine; R4 and R5 are hydrogen or lower alkyl of 1 to 8 carbon atoms; one of R1 and R8 is selected from the group consisting of C 1 to 8 lower alkyl, C 1 to 8 substituted lower alkyl, C 2 to 8 lower alkenyl, 2 to 8 substituted lower alkenyl carbon atoms, aryl, substituted aryl, heteroaryl whose heteroaryl is an aromatic heterocyclic ring system containing up to two rings, substituted heteroaryl whose heteroaryl is an aromatic heterocyclic ring system containing up to two rings, heterocycle whose heterocycle is a hydrocarbon of 5 8-membered, mono- or bicyclic, aromatic or non-aromatic, where 1 to 3 carbon atoms are substituted by an R 1 OR 8 I heteroatom chosen from a nitrogen, oxygen or sulfur atom, substituted heterocycle whose heterocycle is a hydrocarbon aromatic or non-aromatic 5 to 8 membered, mono or bicyclic, where 1 to 3 carbon atoms are replaced by a hetero atom chosen from a nitrogen, oxygen or az atom ufre, cycloalkyl, substituted cycloalkyl, cycloalkenyl and substituted cycloalkenyl and the other is hydrogen, one of R6 and R7 is selected from the group consisting of lower alkyl with 1 to 8 carbon atoms, lower alkyl substituted with 1 to 8 carbon atoms, lower alkenyl with 2 to 8 carbon atoms, lower alkenyl substituted with 2 to 8 carbon atoms, aryl, substituted aryl, heteroaryl, whose heteroaryl is an aromatic heterocyclic ring system containing up to two rings, substituted heteroaryl whose heteroaryl is a system of aromatic heterocyclic ring containing up to two rings, heterocycle whose heterocycle is a 5- to 8-membered aromatic or non-aromatic hydrocarbon, mono- or bicyclic, where 1 to 3 carbon atoms are substituted by a hetero atom chosen from a nitrogen atom, oxygen or sulfur, substituted heterocycle whose heterocycle is a 5- to 8-membered aromatic or non-aromatic hydrocarbon, mono or bicyclic, where 1 to 3 at carbon atoms are substituted by a heteroatom chosen from a nitrogen, oxygen or sulfur atom, cycloalkyl, substituted cycloalkyl, cycloalkenyl and substituted cycloalkenyl and the other is hydrogen, cyano or lower alkyl with 1 to 8 carbon atoms; R2 is selected from the group consisting of hydrogen, lower alkyl with 1 to 8 carbon atoms, and substituted lower alkyl with 1 to 8 carbon atoms; R3 is selected from the group consisting of oxygen, sulfur, and NNH (C = O) OR9; R9 is C 1 -C 8 lower alkyl or C 1 -C 8 substituted lower alkyl; and their pharmaceutically acceptable salts and esters. in which |
| priorityDate | 2006-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1386.