| abstract |
Compound of formula (1) below, or pharmaceutically acceptable salt thereof: where: A. A is selected from the group consisting of the substituents of formulas 2 to 7 below: where R1 is hydrogen or substituted (C1-C4) alkyl or not substituted; and X is carbon or nitrogen; where R2 is hydrogen or substituted or unsubstituted (C1-C4) alkyl; where R3 is hydrogen or substituted or unsubstituted alkyl, cycloalkyl, aryl or heteroaryl; and R'3 is hydrogen, CF3; where R4 is hydrogen, halogen or substituted or unsubstituted (C1-C4) alkyl, or is selected from the substituents of formulas 6a and 6b below: where R5 is hydrogen, halogen or substituted or unsubstituted (C1-C4) alkyl; and X is oxygen, sulfur or sulfone; where R6 is halogen or substituted or unsubstituted (C1-C4) alkyl; B. B is selected from the group consisting of the substituents of formulas 8 to 11 below: where R7, R8, R9 and R10 are each independently hydrogen, halogen or substituted or unsubstituted (C1-C4) alkyl; where R11, R12 and R13 are each independently hydrogen, halogen or substituted or unsubstituted (C1-C4) alkyl and Y is oxygen, sulfur or SO2; where R14 and R15 are each independently hydrogen, halogen, or substituted or unsubstituted (C1-C4) alkyl; and Z is -CH- or oxygen, when Z is oxygen, R14 does not exist; where R17 is substituted or unsubstituted (C1-C4) alkyl. |