http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2345016-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a9e6421e9257148abad101e1ce6c162 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate | 2007-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2010-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61cdc68206eff9d158a7c0a95c471cfc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72ab985c0dba63d4ed6dcfdca8635053 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc2d3364e1db9df102f5ad8c900b721a |
| publicationDate | 2010-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2345016-T3 |
| titleOfInvention | DERIVATIVES OF 2-ARIL-6-PHENYL-IMIDAZO (1,2-A) PIRIDINAS, ITS PREPARATION AND ITS APPLICATION IN THERAPEUTICS. |
| abstract | Compound that responds to formula (I): ** (See formula) ** in which: - R1 represents: a phenyl group or a naphthyl group, these two groups being optionally substituted with one or several atoms or groups independently selected from each other among the following atoms or groups: halogen, (C1-C6) alkyl, cycloalkyl (C3-C7), cycloalkyl (C3-C7) alkylene (C1-C3), haloalkyl (C1-C6), alkoxy ( C1-C6), cycloalkoxy (C3-C7), cycloalkyl (C3-C7) alkylene (C1-C3) -oxy, haloalkoxy (C1-C6), thioalkyl (C1-C6), -S (O) alkyl (C1- C6), -S (O) 2 (C1-C6 alkyl), hydroxyl, cyano, nitro, hydroxyalkylene (C1-C6), NRaBalkylene (C1-C6), alkoxy (C1-C6) alkylene (C1-C6) - oxy, NRaRb, CONRaRb, SO2NRaRb, NRcCORd, OC (O) NRaRb, NRcC (O) ORe, NRcSO2Re, arylalkylene (C1-C6), aryl or heteroaryl, the aryl or heteroaryl being optionally substituted with one or more substituents selected from one or more substituents halogen, a (C1-C6) alkyl, cycloalkyl (C3-C7), cycloalkyl (C3-C7) -alkylene- (C1-C3), haloalkyl (C1-) group C6), (C1-C6) alkoxy, (C1-C6) haloalkoxy, NRaRb, hydroxyl, nitro or cyano; R2 and R3 represent, independently of each other, a hydrogen atom, a (C1-C6) alkyl, cycloalkyl (C3-C7) or cycloalkyl (C3-C7) alkylene (C1-C3) group, this group being optionally substituted with an Rf group; an aryl group, the aryl being optionally substituted with one or more substituents chosen from a halogen, a (C1-C6) alkyl, cycloalkyl (C3-C7), cycloalkyl (C3-C7) alkylene (C1-C3), haloalkyl ( C1-C6), (C1-C6) alkoxy, halo (C1-C6) alkoxy, NRaRb, hydroxyl, nitro or cyano; R4 represents: a hydrogen atom, a (C1-C6) alkyl, cycloalkyl (C3-C7) or cycloalkyl (C3-C7) alkylene (C1-C3) group, this group being optionally substituted with an Rf group; an aryl group, the aryl being optionally substituted with one or more substituents chosen from a halogen, a (C1-C6) alkyl, cycloalkyl (C3-C7), cycloalkyl (C3-C7) alkylene (C1-C3), haloalkyl ( C1-C6), alkoxy (C1-C6), cycloalkoxy (C3-C7), cycloalkyl (C3-C7) alkylene (C1-C3) -oxy, haloalkoxy (C1-C6), NRaRb, hydroxyl, nitro, cyano, alkyl (C1-C6) (CO) -, CONRaRb, NRcCORd, OC (O) NRaRb, NRcC (O) ORe or aryl, the aryl being optionally substituted with one or more substituents chosen from a halogen, a (C1-C6) alkyl group ), cycloalkyl (C3-C7), cycloalkyl (C3-C7) alkylene (C1-C3), haloalkyl (C1-C6), alkoxy (C1-C6), haloalkoxy (C1-C6), NRaRb, hydroxyl, nitro or cyano ; Ra and Rb represent, independently of each other, a hydrogen atom or a (C1-C6) alkyl, cycloalkyl (C3-C7), cycloalkyl (C3-C7) alkylene (C1-C3), arylalkylene (C1-C6) group ) or aryl; or Ra and Rb together form, with the nitrogen atom that carries them, an azetidine, pyrrolidine, piperidine, azepine, morpholine, thiomorpholine, piperazine, homopiperazine group, this group being optionally substituted with a (C1-C6) alkyl, cycloalkyl group (C3-C7), cycloalkyl (C3-C7) alkylene (C1-C6), aryl or arylalkylene (C1-C6); Rc and Rd represent, independently of each other, a hydrogen atom or a (C1-C6) alkyl, cycloalkyl (C3-C7), cycloalkyl (C3-C7) alkylene (C1-C3), arylalkylene (C1-C6) group ), aryl; or Rc and Rd together form an alkylene group (C2-C5); Re represents a (C1-C6) alkyl, (C3-C7) cycloalkyl, (C3-C7) cycloalkyl (C1-C3) alkylene, (C1-C6) arylalkylene, aryl group; or Rc and Re together form an alkylene group (C2-C5); Rf represents a halogen atom, a (C1-C6) alkoxy, haloalkoxy (C1-C6), cycloalkoxy (C3-C7), cycloalkyl (C3-C7) alkylene (C1-C6) -oxy, hydroxyl, cyano, NRaRb group , C (O) NRaRb, NRcCORd, OC (O) NRaRb, NRcCOORe, SO2NRaRb, NRcSO2Re, aryl-alkylene (C1-C6), aryl, the aryl being optionally substituted with one or more substituents chosen from a halogen, an alkyl group (C1-C6), cycloalkyl (C3-C7), cycloalkyl (C3-C7) -alkylene (C1-C3), haloalkyl (C1-C6), alkoxy (C1-C6), haloalkoxy (C1-C6), NRaRb, hydroxyl, nitro or cyano; in the form of base or acid addition salt. |
| priorityDate | 2006-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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