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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-06
filingDate 2006-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2010-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f178cbdbeb17f05e901c8e207c2585f0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_548b9ec4c88fab6e41b409979ae03f79
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publicationDate 2010-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2342788-T3
titleOfInvention PROCESS FOR THE PREPARATION OF ROSUVASTATIN AND INTERMEDIATES.
abstract Process for the preparation of rosuvastatin, of formula I: ** (See formula) ** comprising one of the following processes: a) the reaction of a compound of formula II: ** (See formula) ** in which R represents (C1-4) alkyl except the tert-butyl group, by alkaline hydrolysis, to produce a compound of formula III: ** (See formula) ** and then reaction with an organic or inorganic base to form a salt , removal of the acetonide group and reaction with calcium chloride in a base; or b) the reaction of a compound of formula III: ** (See formula) ** with an organic or inorganic base to form a salt, removal of the acetonide group and reaction with calcium chloride in a base; or c) the reaction of a salt of a compound of formula III: ** (See formula) ** formed with an organic or inorganic base, by removing the acetonide group and reacting with calcium chloride in a base.
priorityDate 2005-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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