http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2341517-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33313e83972b55716428b756d0a5408d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-13 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 |
| filingDate | 2008-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7810baa8d0bfc72a7b5b78e5f6842d70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06a89d49d59d0ce0ab5a606082056196 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25b2cdc27e572d054d954ec1287727e6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_beba0e030a3a220ab121af1bbbc7cec2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6af421fa73984dbeee06454979cbfac1 |
| publicationDate | 2011-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2341517-B1 |
| titleOfInvention | USE OF AN INHIBITOR COMPOUND OF THE ACTIVATION OF THE ERK 1/2 ENZYME IN THE TREATMENT OF NEURODEGENERATIVE DISEASES. |
| abstract | Use of a compound that inhibitsnactivation of the enzyme Erk1 / 2 in the treatment of diseasesnneurodegenerativen n n The present invention relates to thenuse of a compound of formula (I) or of a saltnpharmaceutically acceptable thereof as active ingredient fornpreparation of a medicine, in particular to be used innthe treatment of diseases mediated by the activation ofnErk1 / 2 protein kinase, for example diseasesnneurodegeneratives such as Alzheimer's disease and dementiasnrelated, epilepsy, Parkinson's disease,nHuntington's disease or stroke. The compound of formula (I)nefficiently inhibits the activation of the Erk1 / 2 enzyme induced bynthe tissue plasminogen activator (tPA) and also inhibitsneffective apoptosis generated by the peptidenβ-amyloid. |
| priorityDate | 2008-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 178.