http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2341517-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e94a157678aee94e93e420a5eed90e66 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-13 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 |
filingDate | 2008-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e90662a5ef67159531b3da204a1d8d76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e64add54fafbc97eeaf028442f3b056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74cff9aa683af8a931571ce4e785a648 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa26e6554e43df7e4a2ddddc6cdf8af2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99d1b783d697ad1c3b2e36d0326c5c86 |
publicationDate | 2010-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2341517-A1 |
titleOfInvention | USE OF AN INHIBITOR COMPOUND OF THE ACTIVATION OF THE ERK 1/2 ENZYME IN THE TREATMENT OF NEURODEGENERATIVE DISEASES. |
abstract | Use of a compound that inhibitsnactivation of the enzyme Erk1 / 2 in the treatment of diseasesnneurodegenerativen n n The present invention relates to thenuse of a compound of formula (I) or of a saltnpharmaceutically acceptable thereof as active ingredient fornpreparation of a medicine, in particular to be used innthe treatment of diseases mediated by the activation ofnErk1 / 2 protein kinase, for example diseasesnneurodegeneratives such as Alzheimer's disease and dementiasnrelated, epilepsy, Parkinson's disease,nHuntington's disease or stroke. The compound of formula (I)nefficiently inhibits the activation of the enzyme induced Erk1 / 2nby the tissue plasminogen activator (tPA) and also inhibitsneffectively apoptosis generated by the peptidenβ-amyloid. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011147999-A1 |
priorityDate | 2008-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 180.