http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2341008-T3
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24aca9ded2638ea793d05360dde7a4a0 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C315-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C315-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C317-46 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C319-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C317-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C315-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C315-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-62 |
filingDate | 2004-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2010-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6b7b94c8d4383a99b0511eda6cf9569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84d6adc758302171e296ad48b3769189 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a41e73d432f28eefa3d3196f812b0b6f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba22a36b0ed961b59587894e8faa51c8 |
publicationDate | 2010-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2341008-T3 |
titleOfInvention | PROCEDURE FOR DRIVING BICALUTAMIDE AND PROCEDURE FOR PURIFICATION OF INTERMEDIATE PRODUCTS FOR THE SAME. |
abstract | Process for producing bicalutamide of formula (4): ** (See formula) ** comprising Step A, which comprises the reaction of compound (1) of formula (1) ** (See formula) ** with peroxycarboxylic acid, to obtain the compound (2) of formula (2); ** (See formula) ** Step B, which comprises the reaction of said compound (2) with 4-fluorothiophenol to obtain crude crystals of the compound (3) of formula (3); ** (See formula) ** comprising 0.06 to 0.05% of 4 '' - cyano-3- (4-fluorophenylthio) -2-methyl-3 '' - trifluoromethylpropionanilide, dissolve the crude crystals in a solvent, and crystallize to obtain purified crystals of the compound (3), and step C, which comprises the reaction of the compound (3) and of the percarboxylic acid to obtain bicalutamide. |
priorityDate | 2003-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 51.