http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2339411-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f85681162022797de52846bd2fc56827 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1055 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-581 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-566 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566 |
| filingDate | 1999-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2010-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efcbab3b738c6203214eaa504ffd484a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b1f9e11687982319f722e0bbedfd317 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80dea2965932fb4e0841f043a5988e3a |
| publicationDate | 2010-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2339411-T3 |
| titleOfInvention | COMPLEMENTATION TESTS OF PROTEIN FRAGMENTS. |
| abstract | Method that uses a protein complement / universal indicator system (PAC / URS) assay for the detection and localization of a ligand of a cellular receptor, including said method: (a) the generation of a first nucleic acid vector encoding a first fusion product, comprising: (i) a first fragment of a first PCA / URS indicator molecule, and (ii) a second molecule, fused with said first fragment, comprising a first subdomain of the erythropoietin receptor; (b) the generation of a second nucleic acid vector encoding a second fusion product, comprising: (i) a second fragment of said first PCA / URS indicator molecule, and (ii) a third molecule, fused with said second fragment, comprising a second subdomain of said erythropoietin receptor, and wherein said second subdomain may be the same as said first subdomain, or different from said first subdomain; (c) transfection of prokaryotic or eukaryotic cells with said first and second nucleic acid vectors; and (d) verification in said transfected cells of the PCA / URS indicator activity, said activity indicating the first and second fragment of the PCA / URS molecule mediated by the interaction of said first and second erythropoietin receptor subdomains, said association being induced by linking said receptor with said ligand, wherein said PCA / URS indicator molecule is a polypeptide encoded by a gene that has been dissected rationally into at least two fragments encoding, respectively, said first fragment and said second fragment of said PCA / URS indicator molecule. |
| priorityDate | 1998-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 589.