abstract |
A compound with human P-selectin affinity, comprising a peptide with an amino acid sequence XAxA3A1A2A1Y, in which: A1 is D- or L-cysteine (C), D- or L-methionine (M) or D- or L-valine (V); A2 is D- or L-aspartic acid (D); A3 is D- or L-phenylalanine (F), D- or L-tyrosine (Y) or D- or L-tryptophan (W); AX is a D- or L-amino acid; and wherein X marks the N-terminal side of said sequence and Y marks the C-terminal side of said sequence or in which X and Y together can form a cyclic system. |