http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2337254-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_27a71ddaaa2f5a8c228fc6cb3f3b3098 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 |
| filingDate | 2004-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2010-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53209bf3860bcaf8fc2cacc965ceb4b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b8f1d7ca48b85e2900481373e2c7f5e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44766f4c10b7f6ca875b8d40baabb7df http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48255e35a24b49f1ade64a26568aeb15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_337ce9080a001ce96699c8efb0496d38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74dafeae01280c8d3efcf123503143a3 |
| publicationDate | 2010-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2337254-T3 |
| titleOfInvention | CARBOXAMIDE DERIVATIVES |
| abstract | A compound of formula (I), ** (See formula) ** or a pharmaceutically acceptable salt or solvate thereof, wherein, P is phenyl, pyridyl, pyrimidinyl, piperazinyl or cyclohexyl; W, X and Y form a 5-membered nitrogen-containing heteroaromatic ring in which W, X and Y can be selected from CR1a, NR1b, N, S and O; R1a and R1b are independently -H, C 1-6 alkyl, C 1-6 cycloalkyl, C 3-6 cycloalkyl-C 1-6 alkyl, aryl, C 1-6 arylalkyl, C 1-6 aryloxyalkyl, - (CH 2) xOR 4 or - (CH 2) xNR4R5; R2 is -H, C1-6 alkyl, C1-6 alkoxy or halo; R2a is C1-6 alkyl, C1-6 alkoxy, halo or CF3; R2b is C1-6 alkyl, C1-6 alkoxy, halo or CF3; R3 is -H, halo, C1-6 alkyl, C1-6 alkoxy, C3-6 cycloalkyl, or aryl in which said aryl group may be optionally substituted with one or more R2a groups; heteroaryl wherein said heteroaryl group may be optionally substituted with one or more R2b groups; C 1-6 arylalkyl, C 1-6 arylalkoxy, C 3-6 cycloalkyl, C 1-6 alkyl, C 3-6 cycloalkyl, C 1-6 alkoxy, -CN, -NO2, -OH, -OCF3, -CF3, -NR4R5, -S (O) mR6, -S (O) 2NR4R5, -OS (O) 2R6, -OS (O) 2CF3, -O (CH2) xNR4R5, -O (CH2) xOR4-C (O) CF3, -C (O ) -C 1-6 alkyl, -C (O) -C3-6 cycloalkyl, -C (O) -C 1-6 alkyl, -C (O) Ar, -C (O) (CH2) xOR6, -C (O ) (CH2) xNR4R5, -C (O) C1-6 alkoxy, -C (O) NR4R5, - (CH2) xC (O) -C 1-6 alkoxy, - (CH2) xOC (O) R6, - (CH2 ) xOR6, - (CH2) xNR4R5, - (CH2) xC (O) NR4R5, - (CH2) xN (R4) C (O) R6, - (CH2) xS (O) 2NR4R5, - (CH2) xN (R4 ) S (O) 2R6, -ZAr, - (CH2) xS (O) 2R6, - (OCH2) xS (O) 2R6, -O (CH2) xS (O) 2R6, -N (R4) S (O) 2R6, -N (R4) C (O) R6 or - (CH2) xC (O) C1-6 alkyl; wherein, when one of R 3 is phenyl it may be optionally substituted with one or more halo or heteroaryl atoms optionally substituted with C 1-6 alkyl; R4 and R5 may be the same or different and represent -H or C1-6 alkyl or R4 and R5 together with the nitrogen atom to which they are attached form a heterocyclic ring; R6 is -H, C1-6 alkyl or aryl; R7 is -H, C1-6 alkyl or aryl; Ar is aryl or heteroaryl; m is 0, 1 or 2; r is 0, 1, 2 for 3; s is 0, 1, 3, 4, 5 or 6; x is 0, 1, 3, 4, 5 or 6; and Z is a bond, O, S, NR7 or CH2; wherein the term "aryl" as a group or as part of a group refers to a 5-6 membered monocyclic carbocyclic aromatic radical or to an 8-10 membered fused bicyclic carbocyclic aromatic radical, the term "heteroaryl" as a group or as part of a group refers to a stable 5-7 membered monocyclic aromatic ring or a stable 7 to 10 membered bicyclic heterocyclic aromatic ring consisting of carbon atoms and 1 to 4 heteroatoms independently selected from N, O and S; and the terms "heterocyclyl" and "heterocyclic" as a group or part of a group refers to stable heterocyclic non-aromatic individual and condensed rings containing one or more heteroatoms independently selected from nitrogen, oxygen and sulfur. |
| priorityDate | 2003-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 189.