http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2335229-T3
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d9e9bb060c56c2598e99bc95c6391ca1 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P41-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-02 |
filingDate | 2006-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2010-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_765608676728d0603c277ed3161d57b0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be74da1233a1b1ac6c60c798bb67251a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79c618df31257391858e0f47418e67bc |
publicationDate | 2010-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2335229-T3 |
titleOfInvention | PROCEDURE FOR ENANTIOSELECTIVE ENZYMATIC REDUCTION OF KEY COMPOSITIONS. |
abstract | Procedure for the enantioselective enzymatic reduction of keto compounds of general formula I (I) R1-C (O) -R2 in which R1 represents one of the moieties 1) -alkyl (C1-C20), being straight chain or chain alkyl branched, 2) -alkenyl (C2-C20), being straight chain or branched chain alkenyl and if necessary contains up to four double bonds, 3) -alkynyl (C2-C20), being straight chain or branched chain alkynyl and if necessary it contains up to four triple bonds, 4) -aryl (C6-C14), 5) -alkyl (C1-C8) -aryl (C6-C14), 6) -heterocycle (C5-C14), which is not substituted or mono, di or trisubstituted with -OH, halogen, -NO2 and / or -NH2, or 7) -cycloalkyl (C3-C7); wherein the moieties mentioned above under 1) to 7) are unsubstituted or are mono, di or trisubstituted independently of each other with -OH, halogen, -NO2 and / or -NH2, and R2 represents one of moieties 8) - (C1-C6) alkyl, being straight chain or branched chain alkyl, 9) -alkyl (C2-C6), being straight chain or branched chain alkenyl and if necessary contains up to three double bonds, 10) -alkynyl (C2-C6), being straight chain or branched chain alkynyl and if necessary contains two triple bonds, or 11) -C1-C10 alkyl-C (O) -O-C1-C6 alkyl, being linear or branched chain alkyl and is unsubstituted or is mono, di or trisubstituted with -OH, halogen, -NO2 and / or -NH2, wherein the moieties mentioned above under 8) to 11) are unsubstituted or are mono , di or trisubstituted independently of each other with -OH, halogen, -NO2 and / or -NH2, characterized in that a liquid single-phase mixture comprising (a) at least 5% e n weight / volume of a compound of formula (I), (b) at least 15% by volume of 2-propanol and / or 2-butanol, and (c) water is treated with an R-specific oxide reductase in the presence of a cofactor, to form a chiral hydroxy compound of general formula II (II) R1-CH (OH) -R2 in which R1 and R2 have the meaning indicated above, the cofactor being regenerated by the oxidation of 2-propanol and / or 2 -butanol. |
priorityDate | 2005-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 956.