http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2334796-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c286c5834f71d1d317b6d359f623fb31 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J23-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-18 |
| filingDate | 2004-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2010-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f846de4ed31157abf678931b7a432cd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d7d204bfc44738bf0421991473a2cd2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5436e6a40c2333edbc381be10ec2efcb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a17c7c652964f58b5c5d09cf4ee55cfd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77b61bb6fa064eaf0a835ea36709affc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1d5f516b1c2add25d0593c6bfc9a47d |
| publicationDate | 2010-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2334796-T3 |
| titleOfInvention | NEW PREPARATION PROCEDURE FOR 3-FLUORATED QUINOLEINS. |
| abstract | Process for preparing 3-fluorinated quinoleins of general formula (I): ** (See formula) ** in which R1, R2, R3 and R4, identical or different, represent: - a hydrogen or fluorine atom; - a linear, branched or cyclic alkyl radical, optionally substituted by one to three fluorine atoms, by an OR5 group in which R5 represents a linear or branched alkyl radical, a hydrogen atom or a hydroxy radical protecting group, or by a group NR''R '' '' in which R '' and R '' '', identical or different, represent a linear or branched alkyl radical, a hydrogen atom or a protecting group of the amino radical; - an OR6 group, in which R6 represents a hydrogen atom, a phenol protecting group or a linear or branched alkyl radical, optionally substituted by one to three fluorine atoms, by an OR5 or NR''R '' group '', as defined above; - a group NR''1R '' '' ,, in which R''1 and R '' '' 1, have the values of R '' and R '' '' or represent a substituted linear or branched alkyl radical by one to three fluorine atoms, by an OR5 group as defined above or by a group NR''R '' '' as defined above; - a CO2Ra group, in which Ra represents a hydrogen atom, a linear or branched alkyl radical or a carboxy radical protecting group; - a phenyl radical or a heteroaryl radical, optionally substituted by one or more of the above-mentioned substituents, characterized in that a compound of general formula (IV) is subjected: ** (See formula) ** in which R1, R2, R3 and R4 are defined as above, to a Hofmann degradation to obtain a compound of general formula (III): ** (See formula) ** in which R1, R2, R3 and R4 are defined as above, which are treated in the conditions that allow the formation of the diazonium salt of general formula (II): ** (See formula) ** in which R1, R2, R3 and R4 are defined as above, which are heated in an inert organic solvent. |
| priorityDate | 2003-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 127.