| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1b74695f4c6259a8598b722c1ef6eefa |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0318
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-28 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4747
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-66 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 |
| filingDate |
2007-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_905a965bcf318e2262c57fab9e089e57
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72d6037ee8a23ee66d720df650bb2fcd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_875ae3976c431c9b913b0bfe67697510 |
| publicationDate |
2010-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2334608-A1 |
| titleOfInvention |
METHOD FOR THE IDENTIFICATION OF POTENTIALLY USEFUL COMPOUNDS IN THE TREATMENT OR PREVENTION OF NEURODEGENERATIVE DISEASES. |
| abstract |
Method for the identification of compounds thatninduce or inhibit endoplasmic reticulum stress or stressnoxidativen n n The present invention relates to a methodnfor the identification of producing compounds or inhibitors ofnendoplasmic reticulum stress or oxidative stress. Sayingnmethod is based on the transformation of cells stablynwith a vector that expresses a reporter gene under the control of the genenDDIT3 (also called CHOP). This promoter includes thennucleotides from -1626 to +60 of said gene, having two variantsnof it: -1507 C / G. While the variant-1507nC is not activated under conditions of oxidative stress, -1507 GnRespond to this stimulus in an accused manner. On the other hand, bothnpromoters are activated in reticulum stress situationnendoplasmic, or in a combined situation of both conditions. |
| priorityDate |
2007-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |