| abstract |
Compound that responds to the general formula (I) ** (See formula) ** in which A is chosen from one or more groups X, Y and / or Z; X represents a methylene group optionally substituted with one or two C1-6 alkyl, C3-7 cycloalkyl or C3-7 cycloalkyl-C1-3 alkylene groups; Y represents either a C2-alkenylene group optionally substituted with one or two C1-6 alkyl, C3-7 cycloalkyl or C3-7 cycloalkyl-C1-3 alkylene groups; either a C2 alkynylene group; Z represents a group of formula: ** (See formula) ** m represents an integer ranging from 1 to 5; p and q represent whole numbers and are defined so that p + q is a number that goes from 1 to 5; n represents an integer ranging from 1 to 7; R1 represents a group R2 optionally substituted with one or more groups R3 and / or R4; R2 represents a group selected from pyridinyl, pyrimidinyl, pyridacinyl, pyrazinyl, triacinyl, pyrrolyl, furanyl, thienyl, imidazolyl, oxazolyl, thiazolyl, pyrazolyl, isoxazolyl, isothiazolyl, oxadiazolyl, thiadiazolyl, triazolyl, tetrazolyl, quinolinequinoline, quinolinequinoline, quinolinequinoline, quinolinequinoline, quinolinequinoline, quinolineloxy, quinolineloxy, quinolinequinoline, naphthalenedinyl, quinolineloxy, naphthalenyl, quinolineloxyquinoline tetrahydroisoquinolinyl, 2-oxo-3,4-dihydroquinolinyl, 1-oxo-3,4-dihydroisoquinolinyl, quinazolinyl, quinoxalinyl, phthalazinyl, cinnolinyl, naphthyridinyl, benzofuranyl, dihydrobenzofuranyl, benzothienyl, dihydrobenzothienyl, indolyl, indolinyl, indazolyl, isoindolyl, benzimidazolyl, benzoxazolyl, benzisoxazolyl, benzothiazolyl, benzisothiazolyl, benzotriazolyl, benzoxadiazolyl, benzothiadiazolyl, pyrrolopyridinyl, furopyridinyl, thienopyridinyl, imidazopyridinyl, oxazolopyridinyl, thiazolopyridinyl, pyrazolopyridinyl, isoxazolopyridinyl and isothiazolopyridinyl; R3 represents a group selected from halogen atoms, cyano, nitro, C1-6 alkyl, C1-6 alkoxy, hydroxyl, C1-6 thioalkyl, fluoroalkyl-C1-6, fluoroalkoxy-C1-6, fluorothioalkyl- groups C1-6, NR5R6, NR5COR6, NR5CO2R6, NR5O2R6, COR5, CO2R5, CONR5R6, SO2R5, SO2NR5R6, -O- (C1-3 alkylene) -O; R4 represents a group chosen from the groups phenyl, phenyloxy, benzyloxy, naphthalenyl, pyridinyl, pyrimidinyl, pyridacinyl or pyrazinyl; the R4 group or groups may be substituted with one or several R3 groups identical or different from each other; R5 and R6 independently represent each other a hydrogen atom or a C1-6 alkyl group, or form with the atom (s) that contain them a cycle chosen from an azetidine, pyrrolidine, piperidine, morpholine, thiomorpholine, azepine or piperazine, this cycle being optionally substituted with a C1-6 alkyl or benzyl group; R 7 represents a hydrogen atom or a C 1-6 alkyl group and R 8 represents a hydrogen atom or a C 1-6 alkyl, C 3-7 cycloalkyl, or C 3-7 cycloalkyl-C 1-3 alkylene group; in the base state, of acid addition salt, hydrate or solvate. |