Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eccd894c99fea2d1c0c8735872bb2309 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6813 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-565 |
filingDate |
2005-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2010-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c5d6693511f4c2ecf1ede446e4c9f26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a34c26740e6a1a8e1ccc749f89a7d3d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36f34d1e8ce71393746fa2038f46156b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34d932271a7b20356777455a2206ae9f |
publicationDate |
2010-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
ES-2332924-T3 |
titleOfInvention |
FUSION PROTEINS FC-INTERFERON-BETA. |
abstract |
An Fc-interferon-β fusion protein with improved folding and reduced aggregation comprising: (i) an immunoglobulin Fc region; and (ii) an interferon protein linked by peptide binding or a peptide binding sequence to the carboxy terminal of the Fc region of immunoglobulin, wherein the interferon protein comprises amino acid substitutions compared to the natural mature interferon sequence at positions 17 and 50 and 131 and 140, or 17 and 57 and 131 and 140. |
priorityDate |
2004-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |