abstract |
A compound of Formula ** (See formula) ** wherein Y is selected from the group consisting of: i) a group of Formula ** (See formula) ** where R1 is a phenyl or pyrimidine ring, pyridine not substituted; a phenyl, pyrimidine or pyridine ring that is mono or independently substituted by halo, trifluoromethyl, cyano, nitro or C1-6 alkyl; an unsubstituted phenylsulfonyl group; a phenylsulfonyl group that is mono or disubstituted in the phenyl ring by halo, trifluoromethyl, cyano, nitro or C1-6 alkyl; unsubstituted bezoyl; a benzoyl group that is mono or disubstituted by halo or C1-6 alkyl; C1-6 alkylcarbonyl; thienylsulfonyl; unsubstituted benzothiazole; or a benzothiazole group that is substituted on the phenyl ring by halo or C1-6 alkyl; ii) a group of the Formula ** (See formula) ** wherein R4 is an unsubstituted phenyl ring; or a phenyl ring that is mono or substituted by halo, trifluoromethyl, cyano, nitro or C1-6 alkyl; and iii) a group of the Formula ** (See formula) ** wherein R 5 is C 3-8 cycloalkylcarbonylamino, and Z is CH; and wherein the curved line containing the link means the point of adhesion of the "Y" group to the glycyl-2-cyanopyrrolidine functional group; or a pharmaceutically acceptable acid addition salt thereof. |