http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2330438-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ceb16dd5c50b42d356bc14635df4bfb6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33c64279a777898880e28ebaa087425c |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-235 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-22 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0676 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 |
| filingDate | 2004-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2009-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab6a4b2e26d88fe9cc3fb25d9069ea1f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_805e474a3c9f355dd0177ceca3370839 |
| publicationDate | 2009-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2330438-T3 |
| titleOfInvention | PROCEDURE FOR THE GENERATION OF BETA CELLS OF LANGERHANS ISLANDS FROM EXOCRINE PANCREATIC CELLS. |
| abstract | In vitro method for generating insulin-producing beta cells from a population comprising exocrine pancreas cells dedifferentiated from a first mammal, said method comprising the steps of: a) providing a population comprising exocrine pancreatic cells dedifferentiated in a culture medium, b) adding one or more gp130 receptor ligands of a second mammal and / or adding one or more epidermal growth factor receptor (EGF) ligands of a third mammal to said culture medium, c) incubating said undifferentiated exocrine pancreatic cells in said culture medium comprising said one or more gp130 receptor ligands and / or said one or more EGF receptor ligands, wherein said one or more EGF receptor ligands are selected from EGF, Transformation Growth Factor-alpha , anfirregulin, betacellulin or Poxvirus Growth Factor, and where said one or more receptor ligands r gp130 are selected from Leukemia Inhibitory Factor (LIF), IL-6, IL-11, OSM oncostatin M (OSM), Ciliary Neurotrophic Factor (CNTF), granulocyte colony stimulating factor (G-CSF), cardiotrophin-1 (CT-1), IL-12 or Leptin. |
| priorityDate | 2003-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 443.