http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2330144-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fb4adbd58784b97f699a4d3d9aaac6ff |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-08 |
| filingDate | 2006-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2009-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_379415f86813ae7081d258575013f245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b8d47878e851e9e4122fee807b66c86b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f198fa52b7b9d2081581f204e4b45abd |
| publicationDate | 2009-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2330144-T3 |
| titleOfInvention | PROCEDURE FOR THE PREPARATION OF 3,7-DIAZA-BICYCLE COMPOUNDS (3.3.1) NONANO. |
| abstract | Process for the preparation of 3,7-diaza-bicyclo [3.3.1] nonane compounds of the formula 1 ** (See formula) ** realizing that R means hydrogen, hydroxyl, C1-C4 alkyl; R1 means C1-C4 alkyl, C6-C10 aryl, pyridinyl-C1-C4 alkyl; R2 means C1-C4 alkyl, C6-C10 aryl; R3 means C1-C4 alkyl and X means C = O or C (OH) 2, (a) by reaction of a dicarboxylic acid ester of the formula (2) ** (See formula) ** with a pyridine-aldehyde of the formula (3) ** (See formula) ** as well as with an amine of the formula (4) R2-NH2 (4) to form a piperidone of the formula (5) ** (See formula) ** and (b) by reaction of the piperidones of the formula (5), obtained in this way, with formaldehyde and with an amine of the formula R1-NH2, with R, R1, R2 and R3 having the meanings mentioned above, characterized in that the step The reaction (a) is carried out in a C2-C4 alcohol and the reaction step (b) is carried out in a C3-C4 alcohol and the resulting reaction water is eliminated by an azeotropic distillation. |
| priorityDate | 2005-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.