abstract |
A compound of formula I ** (See formula) ** in free or salt form, wherein Ar is a phenyl optionally substituted by a halo, C1-C8 alkyl, C1-C8 alkoxy, cyano, nitro, -SO2-alkyl C1-C8, -SO2-NH-C1-C8 alkyl or -SO2-N- (C1-C8 alkyl) 2; X is a bond or -CO-CH2-NH-; Y is -CO-R1-, -CO-R2-S-, -CO-NH- or -SO2-; T is a cyclic group selected from C1-C8 cycloalkyl, phenyl optionally substituted by a halo, C1-C8 alkyl, C1-C8 alkoxy or cyano, and a heterocyclic group having a ring of 5 to 10 atoms wherein at least one of those ring atoms is a nitrogen, oxygen or sulfur atom, said heterocyclic group being optionally substituted by a halo, C1-C8 alkyl optionally substituted by an R3, C1-C8 alkoxy optionally substituted by an R3, phenyl or by a heterocyclic ring 5 or 6 members having at least one ring of nitrogen, oxygen or sulfur atom; R1 and R2 are each a bond or C1-C8 alkylene; and R3 is a 5 or 6 membered phenyl or a heterocyclic ring having at least one nitrogen, oxygen or sulfur atom ring |