| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_07b71571160c289fbf5fc680dfea513f |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-54 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 |
| filingDate |
2001-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2009-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55e178a89a49e1115db1d2b9b688ed79
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51fde31f613443165fa8690cd462f57d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe999c5582bc83ece065c7777a6340cb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e64388e1a080257b9e1862767530a2df
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf5cb3471d5bdf160fe3b10ad1bd88ec |
| publicationDate |
2009-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2329875-T3 |
| titleOfInvention |
PREPARATION PROCEDURE FOR A PHYSIOLOGICALLY ACTIVE POLYPEPTIDE. |
| abstract |
A method of producing an active human IL-18 polypeptide from a human IL-18 precursor polypeptide, comprising: (i) Bicistronically co-expressing caspase 4 or caspase 5 with the human IL-18 precursor polypeptide using a bicistronic expression vector comprising a sequence encoding the human IL-18 precursor followed by a sequence encoding caspase 4 or caspase 5 separated by an intergenic region that includes a Shine-Delgarno sequence; and (ii) Purify the active polypeptide. |
| priorityDate |
2000-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |