| abstract |
A derivative of N-alkoxyalkyl-N, N-dialkylamine represented by the following general formula, or its salt: ** see formula ** in which R 1 and R 2 are the same or different and represent at least one group selected from the group consisting of a hydrogen atom, a halogen atom, an alkyl, aryl, aralkyl, alkoxy, aryloxy, alkylthio, arylthio, alkenyl, alkenyloxy, amino, alkylsulfonyl, arylsulfonyl, carbamoyl or unsubstituted or substituted heterocyclic group, a group unprotected or protected amino, hydroxyl or carboxyl, a nitro group and an oxo group; R 3 and R 4 are the same or different and represent an unsubstituted or substituted alkyl, cycloalkyl or aralkyl group; each of mR5 '' s, mR6 '' alkyl; , nR7 's and nR8' 's are the same or different and represent a hydrogen atom or a group; the D ring represents a 5- or 6-membered heterocyclic ring or a hydrocarbon ring; m represents an integer of 1-5; and n represents an integer from 1-6; where the protecting groups for the amino group refer to acyl groups, aryl groups (C1-6 alkyl), arylthio groups, alkyl- or aryl-sulfonyl groups, di- (C 1-6 alkyl) -C1 alkylidene groups 6, aryl (C 1-6 alkylidene) groups, nitrogen-containing heterocyclic alkylidene groups, cycloalkylidene groups, diaryl- or di-aryl (C 1-6 alkylphosphoryl) groups, oxygen-containing heterocyclic alkyl groups, and substituted silyl groups; the protecting groups for the hydroxyl group refer to acyl groups, C 1-6 alkyl groups, C 2-6 alkenyl groups, aryl groups (C 1-6 alkyl), oxygen-containing and sulfur-containing heterocyclic groups, C-alkoxy groups 1-6- and C1-6 alkyl thio-C1-6 alkyl, C1-6 alkyl and aryl sulfonyl groups, and substituted silyl groups; the protecting groups for the carboxyl group refer to C1-6 alkyl groups, aryl groups, aryl groups (C1-6 alkyl), acyl- (C1-6 alkyl) groups, C1-6 alkyl groups-C1-6 alkyl groups, groups acyloxy- (C1-6 alkyl), heterocycle-C1-6 alkyl groups containing nitrogen, cycloalkyl groups, C 1-6 alkoxy groups, C 1-6 alkyl, aryl groups (C 1-6 alkoxy) - (C 1 alkyl -6), C 1-6 alkyl thio-C 1-6 alkyl groups, arylthio-C 1-6 alkyl groups, C 2-6 alkenyl groups, and substituted silyl groups. |