| abstract |
A diarylurea derivative represented by Formula VI, ** see formula ** any of its enantiomers or any mixture of its enantiomers, or a pharmaceutically acceptable addition salt thereof, where AC represents a heterocyclic ring of the structure ** see formula ** R '' represents hydrogen or C 1-6 alkyl; R 1 represents hydrogen, halo, C 1-6 alkyl, C 3-7 cycloalkyl, C 1-6 haloalkyl, nitro or cyano; R 2 represents halo, C 1-6 alkyl, C 3-7 cycloalkyl, C 1-6 haloalkyl, nitro or cyano; and R 3 and R 4, independently of each other, represent hydrogen, halo, hydroxy, C 1-6 alkoxy, C 1-6 haloalkyl or phenyl; or R 3 and R 4 together form a methylenedioxy ring of the structure -O-CH 2-O-; or R 3 and R 4 together form a benzo-condensed ring, said condensed ring being optionally substituted one or more times with substituents selected from halo, hydroxy, C1-6 alkoxy and C1-6 haloalkyl. |